Peter Luczak was the defending champion, but he lost in the second round against Julian Reister.
Robin Haase won in the final 6–4, 6–2 against Tobias Kamke.
Main article: 2010 Franken Challenge
. . . 2010 Franken Challenge – Singles . . .
Florian Mayer(Second Round)- Simon Greul(Semifinals)
Peter Luczak(Second Round)- Daniel Brands(Second Round)
Dustin Brown(First Round)
Rubén Ramírez Hidalgo(Second Round)- Óscar Hernández(First Round)
- Mikhail Kukushkin(Quarterfinals)
. . . 2010 Franken Challenge – Singles . . .
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